A sequence logo is a graphical representation of an amino acid or nucleic acid multiple sequence alignment. Each logo consists of stacks of symbols, one stack for each position in the sequence. The overall height of the stack indicates the sequence conservation at that position, while the height of symbols within the stack indicates the relative frequency of each amino or nucleic acid at that position. In general, a sequence logo provides a richer and more precise description of, for example, a binding site, than would a consensus sequence.
WebLogo is a web-based application designed to make the generation of sequence logos easy and painless. WebLogo has featured in over 4000 scientific publications.
Schneider TD, Stephens RM. 1990. Sequence Logos: A New Way to Display Consensus Sequences. Nucleic Acids Res. 18:6097-6100
Please do not abuse our server. If you need to create large numbers of logos then you are welcome to download the code and run WebLogo on your own machine. If a request flood compromises the WebLogo server then your IP address will be unceremoniously blocked.
While no permanent records are kept of submitted sequences, we cannot undertake to guarantee that data sent to WebLogo remains secure. Moreover, no guarantees whatsoever are provided about data generated by WebLogo.
Suggestions on how to improve WebLogo are heartily welcomed! Please direct questions to the WebLogo discussion group.